Yes, a level 5th wheel will distribute weight on the trailer axels more evenly, and should tow better. Not to mention, if you make one night stops and don't unhitch the truck, having the trailer level is more comfortable.
Most hitch pin assemblies are adjustable up/down in 2" increments. Not super hard to do, but the assembly is heavy. Some 5th wheel hitches can be also be adjusted up/down. My B&W Companion adjusts in 1" increments.
If you need more adjustment than what the above provides, there are other options.
2013 V 3105
2016 F350 King Ranch CC 6.7 diesel dually