I'm running Michelin LTX M/S2 on my F250 supercab with 8' bed. I'm towing a Voltage V 3105. I've been happy with the tires. They are wearing well, do well in the rain and while towing. They are quiet on the highway, at least I don't hear them over the diesel engine. Ride is fine, considering it's a pickup truck, and not a luxury sedan.
I don't off road with the truck, it's used for pulling the RV and hauling things at home. I don't drive it in the snow either.
2013 V 3105
2016 F350 King Ranch CC 6.7 diesel dually